127 Results for "

Euphorbia peplus Linn.

" in MedChemExpress (MCE) Product Catalog:
Products (127)

127 Results for "Euphorbia peplus Linn." in MCE Product Catalog:

53
Silvestrol
Silvestrol
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53 Publications Verification
Cat. No.: HY-13251
CAS No.: 697235-38-4
Purity:  99.96%
Synonyms: (-)-Silvestrol
Category:  

Agave americana Linn. Natural Products Agavaceae Plants Disease Research Fields Cancer

Target:  

Eukaryotic Initiation Factor (eIF) Apoptosis Autophagy

Silvestrol is a eukaryotic translation initiation factor 4A (eIF4A) inhibitor isolated from Agave americana Linn.. Silvestrol induces autophagy and caspase-mediated apoptosis .
14
Morusin
Morusin
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14 Cited Publications
Cat. No.: HY-N0622
CAS No.: 62596-29-6
Synonyms: Mulberrochromene
Category:  

Anti-aging Flavones Plants Infection other families Flavonoids Phenols Polyphenols Disease Research Fields Inflammation/Immunology

Target:  

NF-κB STAT Bacterial

Morusin is a prenylated flavonoid isolated from Morus alba Linn. with various biological activities, such as antitumor, antioxidant, and anti-bacteria property. Morusin could inhibit NF-κB and STAT3 activity.
12
Vitexin
Vitexin
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12 Cited Publications
Cat. No.: HY-N0013
CAS No.: 3681-93-4
Category:  

Cardiovascular Disease Neurological Disease Anti-aging Flavones Metabolic Disease Plants Flavonoids Leguminosae Phenols Polyphenols Disease Research Fields Trigonella foenum-graecum Linn. Cancer

Target:  

Autophagy

Vitexin is a c-glycosylated flavone, and is found in various medicinal plants species such as Trigonella foenum-graecum Linn. Vitexin has a wide range of pharmacological effects, including anti-oxidant, anti-cancer, anti-inflammatory, anti-hyperalgesic, and neuroprotective effects .
11
Hematoxylin
Hematoxylin
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11 Cited Publications
Cat. No.: HY-N0116
CAS No.: 517-28-2
Synonyms: Natural Black 1; Haematoxylin
Category:  

Leguminosae Caesalpinia sappan L. Other Diseases Phenols Polyphenols Plants Disease Research Fields

Target:  

Amyloid-β

Hematoxylin (Natural Black 1), a naturally occurring flavonoid compound derived from Caesalpinia sappan Linn.. Hematoxylin is a nuclear stain in histology and is also a potent Aβ42 fibrillogenesis inhibitor with an IC50 of 1.6 μM.
11
Resiniferatoxin
Resiniferatoxin
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11 Cited Publications
Cat. No.: HY-N2333
CAS No.: 57444-62-9
Synonyms: (+)-Resiniferatoxin
Category:  

Cardiovascular Disease Euphorbia resinifera O. Berg Monophenols Phenols Euphorbiaceae Plants Disease Research Fields

Target:  

TRP Channel

Resiniferatoxin ((+)-Resiniferatoxin), is a selective agonist of transient receptor potential vanilloid 1 (TRPV1) receptor agonist. Resiniferatoxin can be isolated from the Euphorbia resinifera plant. Resiniferatoxin eliminates TRPV1+ primary sensory afferents and blunt cardiac sympathetic afferent reflex for a relatively long period .
10
Isobavachalcone
Isobavachalcone
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10 Cited Publications
Cat. No.: HY-13065
CAS No.: 20784-50-3
Purity:  99.01%
Synonyms: Corylifolinin; Isobacachalcone
Category:  

Plants Flavonoids Chalcones Leguminosae Phenols Polyphenols Psoralea corylifolia L. Disease Research Fields Glycyrrhiza uralensis Fisch. Cancer

Target:  

Akt Reactive Oxygen Species (ROS) Apoptosis Autophagy

Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM). Isobavachalcone also induces Reactive Oxyen Species (ROS) generation in OVCAR-8 cells and has exhibit cancer anti-promotive and anti-proliferative activity .
5
Ingenol Mebutate
Ingenol Mebutate
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5 Cited Publications
Cat. No.: HY-B0719
CAS No.: 75567-37-2
Synonyms: Ingenol 3-angelate; PEP005
Category:  

Terpenoids Euphorbia peplus Linn. Euphorbiaceae Diterpenoids Plants Disease Research Fields Inflammation/Immunology

Target:  

PKC

Ingenol Mebutate is an active ingredient in Euphorbia peplus, acts as a potent PKC modulator, with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM for PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε, respectively, and has antiinflammatory and antitumor activity.
5
20-Deoxyingenol
20-Deoxyingenol
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5 Cited Publications
Cat. No.: HY-N0866
CAS No.: 54706-99-9
Category:  

Terpenoids Euphorbia kansui T. N. Liou ex S. B. Ho Euphorbiaceae Diterpenoids Plants Disease Research Fields Inflammation/Immunology

Target:  

Autophagy

20-Deoxyingenol, a diterpene, is isolated from the roots of Euphorbia kansui. 20-Deoxyingenol can promote autophagy and lysosomal biogenesis by promoting the nuclear translocation of transcription factor EB (TFEB) in vitro. 20-Deoxyingenol can be used for the research of osteoarthritis (OA) .
4
Asparagusic acid
Asparagusic acid
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4 Cited Publications
Cat. No.: HY-50730
CAS No.: 2224-02-4
Category:  

Infection Liliaceae Ketones, Aldehydes, Acids Plants Disease Research Fields Asparagus officinalis L.

Target:  

Parasite Endogenous Metabolite

Asparagusic acid is a sulfur-containing flavor component produced by Asparagus officinalis Linn., with anti-parasitic effect. Asparagusic acid is a plant growth inhibitor .
2
Methyl vanillate
Methyl vanillate
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2 Cited Publications
Cat. No.: HY-75342
CAS No.: 3943-74-6
Category:  

Microorganisms Monophenols Oryza sativa Linn. Gramineae Phenols Plants

Target:  

Wnt Reactive Oxygen Species (ROS) Endogenous Metabolite

Methyl vanillate, one of the ingredients in Oryza sativa Linn., is a Wnt/β-catenin pathway activator . A benzoate ester that is the methyl ester of vanillic acid. It has a role as an antioxidant and a plant metabolite.
2
Moracin O
Moracin O
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2 Cited Publications
Cat. No.: HY-N3244
CAS No.: 123702-97-6
Category:  

Neurological Disease Phenols Polyphenols Plants Moraceae Disease Research Fields Inflammation/Immunology Morus alba Linn.

Target:  

HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species (ROS)

Moracin O is a 2-arylbenzofuran isolated from the Morus alba Linn. . Moracin O exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin O reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin O has neuroprotective and anti-inflammatory effects .
1
Arnidiol
Arnidiol
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1 Cited Publications
Cat. No.: HY-N4165
CAS No.: 6750-30-7
Category:  

Triterpenes Terpenoids Dendranthema morifolium (Ramat.) Tzvel. Other Diseases Plants Compositae Disease Research Fields

Target:  

Others

Arnidiol is a pentacyclic triterpene isolated from Barleria Longiflora Linn F. .
1
3-Epioleanolic acid
3-Epioleanolic acid
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1 Cited Publications
Cat. No.: HY-N4290
CAS No.: 25499-90-5
Category:  

Triterpenes other families Terpenoids Plants Disease Research Fields Inflammation/Immunology

Target:  

Others

3-Epioleanolic acid is an active component of Verbena officinalis Linn, with anti-inflammatory activity .
1
Vitexin (Standard)
Vitexin (Standard)
0 Images
1 Cited Publications
Cat. No.: HY-N0013R
CAS No.: 3681-93-4
Category:  

Flavonoids Leguminosae Flavones Phenols Polyphenols Plants Trigonella foenum-graecum Linn.

Target:  

Reference Standards Autophagy

Vitexin (Standard) is the analytical standard of Vitexin. This product is intended for research and analytical applications. Vitexin is a c-glycosylated flavone, and is found in various medicinal plants species such as Trigonella foenum-graecum Linn. Vitexin has a wide range of pharmacological effects, including anti-oxidant, anti-cancer, anti-inflammatory, anti-hyperalgesic, and neuroprotective effects .
1
Jolkinolide B
Jolkinolide B
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1 Cited Publications
Cat. No.: HY-N0732
CAS No.: 37905-08-1
Category:  

Euphorbia fischeriana Steud. Terpenoids Euphorbiaceae Diterpenoids Plants Disease Research Fields Cancer

Target:  

IAP Akt Caspase NF-κB TGF-beta/Smad JAK Bacterial Apoptosis

Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud with oral activity. Jolkinolide B downregulates XIAP, cIAP1, cIAP2, and phosphorylated Akt, upregulates Smac, activates caspase-3 and caspase-9, and inhibits NF-κB, TGFβ/smad3 and JAK/STAT3 pathways. Jolkinolide B exerts comprehensive biological effects including inducing cancer cell apoptosis, suppressing inflammatory responses, improving lung function, alleviating hepatic steatosis and eliminating intracellular Mycobacterium tuberculosis. Jolkinolide B can be used for the research of leukemia, histiocytic lymphoma, asthma, metabolic dysfunction-associated steatotic liver disease and tuberculosis .
Protodioscin
Protodioscin
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Cat. No.: HY-N0799
CAS No.: 55056-80-9
Category:  

Leguminosae Plants Endogenous metabolite Disease Research Fields Trigonella foenum-graecum Linn. Cancer Steroids

Target:  

Endogenous Metabolite

Protodioscin, a major steroidal saponin in Trigonella foenum-graecum Linn., has been shown to exhibit multiple biological actions, such as anti-hyperlipidemia, anti-cancer, sexual effects and cardiovascular properties.
Dalbergin
Dalbergin
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Cat. No.: HY-N8347
CAS No.: 482-83-7
Category:  

Dalbergia odorifera T. Chen Monophenols Leguminosae Other Diseases Coumarins Phenols Phenylpropanoids Plants Disease Research Fields

Target:  

Apoptosis

Dalbergin is a composition of the extract from the Dalbergia Sissoo Linn. knot wood. Dalbergin demonstrats notable antioxidant ability .
Obtusin
Obtusin
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Cat. No.: HY-N6057
CAS No.: 70588-05-5
Category:  

Seeds of Cassia tora Linn. Quinones other families Leguminosae Anthraquinones Phenols Polyphenols Plants

Target:  

Monoamine Oxidase

Obtusin, isolated from Cassia obtusifolia Linn seed, is a highly selective and competitive human monoamine oxidase-A (hMAO-A) inhibitor with an IC50 of 11.12 μM and a Ki of 6.15 μM. Obtusin plays a preventive role in neurodegenerative diseases, especially anxiety and depression .
Euphorbia Factor L2
Euphorbia Factor L2
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Cat. No.: HY-N5001
CAS No.: 218916-51-9
Category:  

Gramineae Terpenoids Leptochloa chinensis (Linn.) Nees Diterpenoids Plants Disease Research Fields Cancer

Target:  

Apoptosis

Euphorbia factor L2, a lathyrane diterpenoid isolated from caper euphorbia seed (the seeds of Euphorbia lathyris L.), has been traditionally applied to treat cancer. Euphorbia factor L2 shows potent cytotoxicity and induces apoptosis via a mitochondrial pathway .
Tirucallol
Tirucallol
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Cat. No.: HY-N2556
CAS No.: 514-46-5
Category:  

Triterpenes Euphorbia boetica Terpenoids Euphorbiaceae Plants Disease Research Fields Inflammation/Immunology

Target:  

Others

Tirucallol, a tetracyclic triterpene, is isolated from Euphorbia lacteal latex. Tirucallol has topical anti-inflammatory effect. Tirucallol can suppress ear edema in the mouse model and inhibit nitrite production in lipopolysaccharide-stimulated macrophages .
Assay Types